ZooDDD：用于数字差异显示分析的跨物种数据库。
ZooDDD: a cross-species database for digital differential display analysis.
作者信息
Chen Yun-Ching, Hsiao Chung-Der, Lin Wen-Dar, Hu Chung-Ming, Hwang Pung-Pung, Ho Jan-Ming
机构信息
Institute of Information Science, Academia Sinica, NanKang 115, Taipei, Taiwan, Republic of China.
出版信息
Bioinformatics. 2006 Sep 1;22(17):2180-2. doi: 10.1093/bioinformatics/btl358. Epub 2006 Jul 4.
UNLABELLED
In this article, we combined EST information from the UniGene database and orthologous relationships from the Ensembl database to construct a ZooDDD database. The primary function of ZooDDD is to mine evolutionary conserved, highly expressed, tissue-specific orthologues in model animals. The candidate genes of interest derived from the ZooDDD database will provide biologists with a good step for comparing the expression, functions and evolution of animal genomes.
AVAILABILITY
未标注
在本文中，我们结合了来自UniGene数据库的EST信息和来自Ensembl数据库的直系同源关系来构建一个动物直系同源数据库（ZooDDD）。ZooDDD的主要功能是挖掘模式动物中进化保守、高表达、组织特异性的直系同源物。从ZooDDD数据库中获得的感兴趣的候选基因将为生物学家比较动物基因组的表达、功能和进化提供一个良好的开端。
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