Raidal S R, Shearer P L, Butler R, Monks D
School of Agricultural and Veterinary Sciences, Charles Sturt University, Boorooma St., Wagga Wagga, New South Wales 2678, Australia.
Aust Vet J. 2006 Jun;84(6):213-6. doi: 10.1111/j.1751-0813.2006.tb12803.x.
The clinical signs, radiographic and pathological findings of four histologically similar neoplasms that occurred as unilateral tumours projecting from the left axilla in three galahs (Eolophus roseicapillus) and one sulphur-crested cockatoo (Cacatua galerita) are described. In each case, the main reason for clinical presentation was respiratory distress. All cases were eventually fatal due to airway obstruction with evidence of extensive neoplastic invasion of the lungs, major airways and or humerus in all cases. A diagnosis of airsac cystadenocarcinoma was made in each bird on the basis of gross and histological appearance. The neoplasms were composed of fluid or air-filled sacs of proliferative cuboidal to squamous epithelial cells that stained positively with cytokeratin and negatively with vimentin. This was supported by a thin fibrovascular network although at least some areas in all four birds resembled airsac tissue. In some cases areas of haemorrhage, erythrophagocytosis, haemosiderosis and nodules of haemosiderophage infiltration with acicular cholesterol clefts were present in some parts of the sectioned tissue.
描述了三只粉红凤头鹦鹉（Eolophus roseicapillus）和一只硫冠凤头鹦鹉（Cacatua galerita）左侧腋窝处出现的单侧肿瘤，这四种组织学上相似的肿瘤的临床体征、影像学和病理学发现。在每种情况下，临床表现的主要原因是呼吸窘迫。所有病例最终均因气道阻塞而死亡，所有病例均有肺部、主要气道和/或肱骨广泛肿瘤浸润的证据。根据大体和组织学表现，每只鸟均被诊断为气囊囊腺癌。肿瘤由增殖的立方上皮至鳞状上皮细胞组成的充满液体或空气的囊泡构成，细胞角蛋白染色阳性，波形蛋白染色阴性。尽管所有四只鸟的至少某些区域类似于气囊组织，但有一个薄的纤维血管网络支持这一诊断。在某些情况下，切片组织的某些部位存在出血、红细胞吞噬、含铁血黄素沉着以及伴有针状胆固醇裂隙的含铁血黄素巨噬细胞浸润结节。
