Gardhouse Sara, Pinard Chantale L, Barboza Trinita, Knight Britta, Zaheer Omar A, Susta Leonardo, Beaufrère Hugues
Health Sciences Centre (Gardhouse, Zaheer), Department of Clinical Sciences (Pinard, Barboza, Beaufrère), Department of Pathobiology (Knight, Susta), Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1.
Can Vet J. 2021 Mar;62(3):226-232.
A 34-year-old female greater sulfur-crested cockatoo was referred for suspected left globe rupture. Ophthalmic examination revealed effacement of the anterior chamber and cornea by a large mass. The left eye was enucleated due to suspicion of globe rupture, secondary to a neoplastic process or chronic trauma. Histopathological examination revealed complete effacement of the internal ocular structures by a neoplasm morphologically consistent with an iridociliary adenoma. The diagnosis was confirmed by Periodic acid-Schiff histochemistry and immunohistochemistry for S100, Melan-A/PNL2, and vimentin antigens. The cockatoo recovered well from surgery, with appropriate healing of the enucleation site, and no evidence of recurrence at 1-year follow-up. Key clinical message: To the authors' knowledge, this is the first report of iridociliary adenoma in a greater sulfur-crested cockatoo, and the third report of such a neoplasm in a psittacine species with a description of the use of immunohistochemistry to confirm a diagnosis of a rare tumor in a bird species.
一只34岁的雌性大凤头鹦鹉因疑似左眼球破裂被转诊。眼科检查发现一个大肿块使前房和角膜消失。由于怀疑眼球破裂继发于肿瘤性病变或慢性创伤，左眼被摘除。组织病理学检查显示，肿瘤在形态上与虹膜睫状体腺瘤一致，完全破坏了眼内结构。通过高碘酸希夫组织化学以及针对S100、黑素A/PNL2和波形蛋白抗原的免疫组织化学检查确诊。这只凤头鹦鹉术后恢复良好，眼球摘除部位愈合正常，在1年的随访中没有复发迹象。关键临床信息：据作者所知，这是大凤头鹦鹉虹膜睫状体腺瘤的首例报告，也是鹦鹉科鸟类中该肿瘤的第三例报告，文中描述了使用免疫组织化学来确诊鸟类罕见肿瘤的情况。
