Gramatikov B I, Zalloum O H Y, Wu Y K, Hunter D G, Guyton D L
Johns Hopkins University School of Medicine, Wilmer Ophthalmological Institute, The Krieger Children's Eye Center, Baltimore, Maryland 21287-9028, USA.
J Biomed Opt. 2006 May-Jun;11(3):34025. doi: 10.1117/1.2209003.
For the purpose of vision screening, we develop an eye fixation monitor that detects the fovea by its unique radial orientation of birefringent Henle fibers. Polarized near-infrared light is reflected from the foveal area in a bow-tie pattern of polarization states, similar to the Haidinger brush phenomenon. In contrast to previous devices that used scanning systems, this instrument uses no moving parts. It rather utilizes four spots of linearly polarized light-two aligned with the "bright" arms and two aligned with the "dark" arms-of the bow-tie pattern surrounding the fovea. The light reflected from the fundus is imaged onto a quadrant photodetector, whereby the circular polarization component of the polarization state of each reflected patch of light is measured. The signals from the four photodetectors are amplified, digitized, and analyzed. A normalized differential signal is computed to detect central fixation. The algorithm is tested on a computer model, and the apparatus is tested on human subjects. This work demonstrates the feasibility of a fixation monitor with no moving parts.
为了进行视力筛查,我们开发了一种眼注视监测仪,它通过双折射的亨勒纤维独特的径向取向来检测中央凹。偏振近红外光从中央凹区域以蝴蝶结状的偏振态模式反射,类似于海丁格刷现象。与之前使用扫描系统的设备不同,该仪器没有移动部件。它利用围绕中央凹的蝴蝶结图案中四个线性偏振光斑点——两个与“亮”臂对齐,两个与“暗”臂对齐。从眼底反射的光被成像到象限光电探测器上,从而测量每个反射光斑偏振态的圆偏振分量。来自四个光电探测器的信号被放大、数字化并进行分析。计算归一化差分信号以检测中心注视。该算法在计算机模型上进行了测试,该设备在人体受试者上进行了测试。这项工作证明了一种无移动部件的注视监测仪的可行性。