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苯乙烯的微生物降解:生物化学、分子遗传学及生物技术应用前景

Microbial degradation of styrene: biochemistry, molecular genetics, and perspectives for biotechnological applications.

作者信息

Mooney Aisling, Ward Patrick G, O'Connor Kevin E

机构信息

Centre for Synthesis and Chemical Biology, School of Biomolecular and Biomedical Sciences, College of Life Sciences, University College Dublin, Belfield, Dublin 4, Ireland.

出版信息

Appl Microbiol Biotechnol. 2006 Aug;72(1):1. doi: 10.1007/s00253-006-0443-1. Epub 2006 Jul 6.

Abstract

Large quantities of the potentially toxic compound styrene are produced and used annually by the petrochemical and polymer-processing industries. It is as a direct consequence of this that significant volumes of styrene are released into the environment in both the liquid and the gaseous forms. Styrene and its metabolites are known to have serious negative effects on human health and therefore, strategies to prevent its release, remove it from the environment, and understand its route of degradation were the subject of much research. There are a large number of microbial genera capable of metabolizing styrene as a sole source of carbon and energy and therefore, the possibility of applying these organisms to bioremediation strategies was extensively investigated. From the multitude of biodegradation studies, the application of styrene-degrading organisms or single enzymes for the synthesis of value-added products such as epoxides has emerged.

摘要

石化和聚合物加工行业每年都会生产和使用大量具有潜在毒性的化合物苯乙烯。正因如此,大量苯乙烯以液态和气态形式释放到环境中。已知苯乙烯及其代谢产物会对人体健康产生严重负面影响,因此,防止其释放、从环境中去除以及了解其降解途径的策略成为了众多研究的主题。有大量微生物属能够将苯乙烯作为唯一的碳源和能源进行代谢,因此,人们广泛研究了将这些生物应用于生物修复策略的可能性。从众多生物降解研究中,已出现了将降解苯乙烯的生物或单一酶应用于合成环氧化物等增值产品的情况。

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