Uzel Asli, Uzel Ilter, Sagliker Yahya, Yildiz Ismail, Halvaci Ilker, Paylar Nuray, Ocal Fatih, Balal Mustafa, Ozkaynak Piril Sagliker, Paydas Saime, Sagliker Cemal, Sagliker Hasan Sabit, Kiralp Necati, Adam Sidik Momin, Esenturk Mustafa, Gocmez Erdal, Taskapan Hulya, Yuksekgonul Musa, Emir Idris, Guler Turgay, Yakar Hasan, Sekin Oktay, Kayali Erkan, Caliskan Sihli, Eskiocak Ali Fuat, Ogruk Bulent, Guzelyurt Tahsin, Kurt Cemal
Cukurova University Dentistry Faculty, Adana, Turkey.
J Ren Nutr. 2006 Jul;16(3):229-32. doi: 10.1053/j.jrn.2006.04.019.
It is well known that secondary hyperparathyroidism may be an extremely severe condition in chronic renal failure, and almost all patients with chronic kidney disease, even in the well-developed countries, encounter every kind of bone abnormalities if they are not treated properly. Although some sporadic cases have been reported of unique facial bone changes, the largest collection of this phenomenon has been reported by Sagliker et al. We also have found 6 of 9 patients who have these changes (Sagliker syndrome) to manifest class II malocclusion of the upper and lower jaws according to dental universally accepted criteria by performing cephalometric studies, x-ray plain films, tomographic procedures, and drawing technology.
众所周知，继发性甲状旁腺功能亢进在慢性肾衰竭中可能是一种极其严重的病症，几乎所有慢性肾病患者，即便在发达国家，如果未得到妥善治疗，都会出现各种骨骼异常。尽管已有一些散发病例报道了独特的面部骨骼变化，但Sagliker等人报道了这一现象的最大病例集。通过进行头影测量研究、X线平片、断层扫描程序和绘图技术，我们还发现9名有这些变化（Sagliker综合征）的患者中有6名根据普遍接受的牙科标准表现出上下颌II类错牙合。
