Heller Debra S, Maslyak Svetlana, Skurnick Joan
Department of Pathology and Laboratory Medicine, UH/E158, UMDNJ-New Jersey Medical School, Newark, NJ 07101, USA.
J Low Genit Tract Dis. 2006 Jul;10(3):137-9. doi: 10.1097/00128360-200607000-00002.
Bacterial vaginosis (BV) is associated with significant morbidity. Bacterial vaginosis is due to an overgrowth of anaerobic organisms in the vagina. It has been postulated that the presence of Trichomonas creates an anaerobic environment that favors BV. Thus, BV should be more frequent in the presence of Trichomonas if Trichomonas is creating a favorable anaerobic environment.
A retrospective review of Pap test reports was performed for a diagnosis of coccobacilli consistent with shift in vaginal flora, that is, the presence of clue cells. Cases were Pap smears with Trichomonas identified. Controls were cases without Trichomonas. Results were analyzed using Fisher exact test.
Four hundred cases were reviewed; 200 with and 200 without Trichomonas. The incidence of BV was significantly higher in the Trichomonas group (46.5%) than in group without Trichomonas (24.5%) (p < .0001.).
The presence of Trichomonas on a Pap smear is associated with an increased incidence of BV. The report of Trichomonas on a Pap smear should prompt clinical consideration that BV may be present.
细菌性阴道病（BV）与严重的发病率相关。细菌性阴道病是由于阴道内厌氧菌过度生长所致。据推测，滴虫的存在会营造有利于BV的厌氧环境。因此，如果滴虫营造了适宜的厌氧环境，那么在有滴虫存在的情况下，BV应该更常见。
对巴氏试验报告进行回顾性分析，以诊断与阴道菌群变化相符的球杆菌，即线索细胞的存在情况。病例为检测出滴虫的巴氏涂片。对照为未检测出滴虫的病例。采用Fisher精确检验分析结果。
共审查了400例病例；200例有滴虫，200例无滴虫。滴虫组BV的发病率（46.5%）显著高于无滴虫组（24.5%）（p <.0001）。
巴氏涂片上有滴虫与BV发病率增加相关。巴氏涂片报告有滴虫时，临床应考虑可能存在BV。
