独活挥发油的气相色谱-质谱联用分析
[GC-MS analysis of essential oils from Radix Angelicae Pubescentis].
作者信息
Yang Xiu-wei, Liu Yu-feng, Tao Hai-yan, Yang Zhi, Xiao Shi-ying
机构信息
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences of Peking University, Beijing, China.
出版信息
Zhongguo Zhong Yao Za Zhi. 2006 Apr;31(8):663-6.
OBJECTIVE
To analyze the constituents of the essential oils from Radix Angelicae Pubescentis planted in a GAP base of the Chinese medica materials, and provide the scientific basis for quality control.
METHOD
The essential oils were extracted by water-steam distillation and separated by GC capillary column chromatography. The components were calculated with normalization method, and were identified by MS detector.
RESULT
229 peaks weredetected, among which 8 compounds have been identified, which made up 78.23% of the total essential oil.
CONCLUSION
In the total essential oils of Radix Angelicae Pubescentis, 3-carene (8.89%), m-cymene (4.99%) and beta-phellandrene (8.35%) as the monoterpenes and its derivatives, and eudesma-4 (14), 11-diene (4.36%), alpha-selinene (1.36%), ledol (1.14%), alpha-bisabolol (6.03%), and 1, 8-dimethyl-4-(1-methylethyl)-spiro[4.5]dec-8-en-7-one (4.37%) as the sesquiterpenes and its derivatives, are main components.
目的
分析中药材GAP基地种植的独活挥发油成分，为质量控制提供科学依据。
方法
采用水蒸气蒸馏法提取挥发油，用气相色谱毛细管柱色谱法分离，采用归一化法计算各成分含量，用质谱检测器进行成分鉴定。
结果
共检测出229个峰，鉴定出8种化合物，占挥发油总量的78.23%。
结论
独活挥发油中，单萜及其衍生物3-蒈烯（8.89%）、间伞花烃（4.99%）和β-水芹烯（8.35%），倍半萜及其衍生物桉叶-4（14），11-二烯（4.36%）、α-芹子烯（1.36%）、喇叭茶醇（1.14%）、α-红没药醇（6.03%）和1,8-二甲基-4-（1-甲基乙基）-螺[4.5]癸-8-烯-7-酮（4.37%）为主要成分。
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