Johnson M O, Gamarel K E, Dawson Rose C
University of California, San Francisco, Center for AIDS Prevention Studies, 50 Beale Street, San Francisco, CA 94105, USA.
AIDS Care. 2006 Aug;18(6):550-3. doi: 10.1080/09540120500241439.
Beliefs about HIV treatment efficacy, adherence self-efficacy, and side effects management are related cross-sectionally to adherence to antiretroviral therapy (ART). However, the role of such expectancies held prior to the initiation of ART is unknown. The purpose of this study was to explore feasibility, satisfaction, and preliminary effects of an intervention to address HIV treatment expectancies. ART naïve participants (N = 26) who were contemplating ART initiation were randomized to a single session group intervention or standard care control condition. The session included an exploration of expectancies; an education about ART efficacy, adherence, and side effects; and guided problem solving around adherence and side effects management. The pilot intervention was feasible and was rated highly satisfactory. Follow-up assessments demonstrated that intervention participants increased adherence self-efficacy and positive side effects expectancies relative to those in the control group (ps<.05). Findings have implications for nursing practice and further research in the area of HIV treatment expectancies and treatment readiness.
关于艾滋病毒治疗效果、坚持治疗的自我效能感以及副作用管理的信念与抗逆转录病毒疗法（ART）的依从性存在横断面关联。然而，在开始抗逆转录病毒治疗之前持有此类预期的作用尚不清楚。本研究的目的是探讨一种针对艾滋病毒治疗预期的干预措施的可行性、满意度和初步效果。考虑开始接受抗逆转录病毒治疗的初治参与者（N = 26）被随机分为单次小组干预组或标准护理对照组。该环节包括对预期的探索；关于抗逆转录病毒治疗效果、依从性和副作用的教育；以及围绕依从性和副作用管理的指导性问题解决。试点干预措施是可行的，且被评为高度满意。随访评估表明，与对照组相比，干预组参与者的坚持治疗自我效能感和积极的副作用预期有所增加（p<0.05）。研究结果对护理实践以及艾滋病毒治疗预期和治疗准备领域的进一步研究具有启示意义。
