Reich Wendy, Huang Hongyan, Todd Richard D
Division of Child Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8134, St. Louis, MO 63110, USA.
J Am Acad Child Adolesc Psychiatry. 2006 Jul;45(7):801-7. doi: 10.1097/01.chi.0000219833.00979.c3.
To determine treatment patterns for youth attention-deficit/hyperactivity disorder (ADHD) symptoms in a general population sample of 1,610 twins.
Twin pairs ages 7 to 17 years and parents ascertained from birth records in the state of Missouri were interviewed using the Missouri Assessment of Genetics Interview for Children between 1996 and 2001. Multivariate logistic regression analyses were used to determine which factors were significant in answering three questions about treatment for ADHD.
Of 302 boys, 177 (58.6%) and 26 of 57 girls (45.6%) who met full DSM-IV criteria for ADHD received stimulant medication in this sample. Of 314 youths, 111 (35.4%) who received stimulant medication did not meet DSM-IV criteria for ADHD. When controlling for comorbidity and other factors, the number of impairing ADHD symptoms and having a cotwin who was also brought to treatment for ADHD correlated with referral or treatment in youths without ADHD. Youths without ADHD who were treated had a large number of ADHD symptoms.
As is shown in earlier studies, children with ADHD are being undertreated. Complex factors, including comorbid disorders and family history of ADHD treatment, affect treatment patterns in the general population.
在1610对双胞胎的普通人群样本中确定青少年注意力缺陷/多动障碍（ADHD）症状的治疗模式。
1996年至2001年间，使用密苏里儿童遗传学访谈评估对来自密苏里州出生记录中确定的7至17岁双胞胎及其父母进行访谈。采用多变量逻辑回归分析来确定哪些因素在回答关于ADHD治疗的三个问题时具有显著性。
在这个样本中，符合ADHD完整DSM-IV标准的302名男孩中有177名（58.6%）以及57名女孩中有26名（45.6%）接受了兴奋剂药物治疗。在314名青少年中，111名（35.4%）接受兴奋剂药物治疗的青少年不符合ADHD的DSM-IV标准。在控制合并症和其他因素时，ADHD症状的损害数量以及有一个也因ADHD接受治疗的双胞胎与未患ADHD的青少年的转诊或治疗相关。接受治疗的未患ADHD的青少年有大量ADHD症状。
如早期研究所示，ADHD儿童的治疗不足。包括合并症和ADHD治疗家族史在内的复杂因素影响普通人群的治疗模式。
