Garatti Andrea, Colombo Tiziano, Russo Claudio, Lanfranconi Marco, Milazzo Filippo, Catena Emanuele, Bruschi Giuseppe, Frigerio Maria, Vitali Ettore
Division of Cardiac Surgery, Department A. De Gasperis, Niguarda Ca'Granda Hospital, Milan, Italy.
Artif Organs. 2006 Jul;30(7):523-8. doi: 10.1111/j.1525-1594.2006.00254.x.
The Impella Recover left direct (LD) is a new intravascular microaxial blood pump, intended as a short-term mechanical support especially in case of acutely reduced left ventricular function. From September 2002 to October 2004, Impella was used to support 12 patients: six patients were supported as bridge-to-heart transplant (HTx); three patients were treated for fulminant acute myocarditis, and three patients for postcardiotomy low-output syndrome. Mean support time was 8.8 +/- 2.3 days. Overall mortality was 50%. Four patients were successfully HTxed; two patients supported as bridge-to-HTx died on left ventricular assist device. Two patients with myocarditis died of septic shock; two patients in the group of postcardiotomy died of multiorgan failure. The latter two patients were slowly weaned from the device, and at 3-months follow-up showed good improvement of the left ventricular function. Our initial experience with Impella Recover LD as mechanical support for patients in cardiogenic shock of various etiology is promising, yielding a good survival in a population of particularly compromised patients.
Impella Recover左心直接型（LD）是一种新型的血管内微轴血泵，旨在作为短期机械支持，特别是在左心室功能急性降低的情况下。从2002年9月至2004年10月，Impella用于支持12例患者：6例患者作为心脏移植（HTx）的过渡；3例患者治疗暴发性急性心肌炎，3例患者治疗心脏术后低心排血量综合征。平均支持时间为8.8±2.3天。总死亡率为50%。4例患者成功接受心脏移植；2例作为心脏移植过渡接受支持的患者在左心室辅助装置上死亡。2例心肌炎患者死于感染性休克；心脏术后组的2例患者死于多器官功能衰竭。后2例患者逐渐脱离该装置，在3个月随访时左心室功能有良好改善。我们使用Impella Recover LD作为各种病因的心源性休克患者机械支持的初步经验很有前景，在特别病情严重的患者群体中取得了良好的生存率。
