青少年早期和晚期未来抑郁的预测因素。

Predictors of future depression in early and late adolescence.

作者信息

van Lang Natasja D J, Ferdinand Robert F, Verhulst Frank C

机构信息

Department of Child and Adolescent Psychiatry, Erasmus Medical Center, Rotterdam, The Netherlands.

出版信息

J Affect Disord. 2007 Jan;97(1-3):137-44. doi: 10.1016/j.jad.2006.06.007. Epub 2006 Jul 11.

Abstract

BACKGROUND

This study examined whether the possibility to predict future DSM-IV depressive disorder can be increased with recurrent screening for depression in community adolescents, compared to single screening in early or in late adolescence. In addition, it examined which depressive symptoms in early and late adolescence predicted future depressive disorder most accurately.

METHODS

Participants from an ongoing longitudinal cohort study were assessed when they were aged between 10 and 15 (early adolescence), and between 14 and 19 (late adolescence), and were followed until they were 20-25 (young adulthood). The Child Behavior Checklist (CBCL) and Youth Self-Report (YSR) were used to screen for depression in early and late adolescence, and CIDI/DSM-IV diagnoses of depressive disorder were used as the outcome measure during follow-up.

RESULTS

Recurrent screening only slightly improved the prediction of future depression, and cognitive and physical symptoms in late adolescence predicted future depression accurately in boys. Sleeping problems in early adolescence predicted future depression in girls.

LIMITATIONS

The main limitation was the retrospective recall of the age of onset of a depressive disorder.

CONCLUSIONS

Recurrent screening for depression did not predict future depressive disorder better than single screening in late adolescence. However, depressive symptoms like sleeping problems predicted future depression quite accurately in adolescent boys and girls. This indicates that it may be useful to screen adolescents for the presence of such symptoms, for instance in school settings, to predict which adolescents are at risk to develop DSM-IV depressive disorder in early adulthood.

摘要

背景

本研究探讨了与在青少年早期或晚期进行单次筛查相比,通过对社区青少年反复进行抑郁症筛查,是否能够提高预测未来《精神疾病诊断与统计手册》第四版(DSM-IV)抑郁症的可能性。此外,还研究了青少年早期和晚期的哪些抑郁症状能够最准确地预测未来的抑郁症。

方法

来自一项正在进行的纵向队列研究的参与者在10至15岁(青少年早期)和14至19岁(青少年晚期)时接受评估,并随访至20至25岁(青年期)。使用儿童行为清单(CBCL)和青少年自我报告(YSR)在青少年早期和晚期筛查抑郁症,并将CIDI/DSM-IV抑郁症诊断作为随访期间的结果指标。

结果

反复筛查仅略微改善了对未来抑郁症的预测,青少年晚期的认知和身体症状能准确预测男孩未来的抑郁症。青少年早期的睡眠问题能预测女孩未来的抑郁症。

局限性

主要局限性在于对抑郁症发病年龄的回顾性回忆。

结论

与在青少年晚期进行单次筛查相比,反复筛查抑郁症并不能更好地预测未来的抑郁症。然而,像睡眠问题这样的抑郁症状在青少年男孩和女孩中能相当准确地预测未来的抑郁症。这表明在青少年中筛查此类症状,例如在学校环境中,以预测哪些青少年在成年早期有患DSM-IV抑郁症的风险,可能是有用的。

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