Johansson K, Malmsjö M, Ghosh F
Department of Ophthalmology, Lund University Hospital, Lund, Sweden.
Br J Ophthalmol. 2006 Oct;90(10):1286-91. doi: 10.1136/bjo.2006.098202. Epub 2006 Jul 12.
To investigate the anatomical and functional results and the complications in eyes operated on using vitrectomy without scleral buckling for all forms of rhegmatogenous retinal detachment (RRD).
All cases of primary RRD at the University Hospital of Lund, Lund, Sweden, treated by one surgeon during a period of 3 years were retrospectively reviewed. In 131 (98%) of 134 consecutive cases, a final follow-up record of 3-14 months was obtained, and these eyes were included in the study. The surgical protocol was tailored for each case and consisted of vitrectomy, laser photocoagulation and tamponade. Preoperative and intraoperative variables were analyses for risk for redetachment and postoperative proliferative vitreoretinopathy (PVR).
Complete reattachment was achieved in 87% of cases (114/131) after one operation and in 95% cases after > or =1 operation. A primary detachment of >1 quadrant was the only significant risk factor for redetachment (p<0.05). The most common cause of redetachment was progressive PVR. Significant risk and factors for PVR postoperatively were a poor preoperative visual acuity and a high number of laser effects during surgery (p<0.05). The visual acuity for the total number of eyes, macula-off eyes, and pseudophakic as well as phakic eyes, improved significantly. The visual acuity for macula-on eyes did not change significantly. Six patients developed ocular hypertension and another 6 an epiretinal membrane. Three patients reported a visual field defect. Increased lens opacification was seen in 64 of the 94 (68%) phakic eyes.
The tailored vitrectomy protocol is well suited to all types of RRD. Increased lens opacification in phakic eyes is common, but visual acuity is considerably improved in phakic as well as pseudophakic eyes. PVR development postoperatively is related to the extent of laser treatment, indicating that the protocol may be even further optimised in the future.
研究采用不伴巩膜扣带术的玻璃体切除术治疗各种类型孔源性视网膜脱离(RRD)的眼部解剖和功能结果以及并发症。
回顾性分析瑞典隆德大学医院一名外科医生在3年期间治疗的所有原发性RRD病例。在连续134例病例中的131例(98%)获得了3至14个月的最终随访记录,这些眼睛被纳入研究。手术方案根据每个病例量身定制,包括玻璃体切除术、激光光凝和眼内填充。分析术前和术中变量以评估再脱离和术后增生性玻璃体视网膜病变(PVR)的风险。
一次手术后87%的病例(114/131)实现了完全复位,≥1次手术后95%的病例实现了完全复位。大于1个象限的原发性脱离是再脱离的唯一显著危险因素(p<0.05)。再脱离最常见的原因是进行性PVR。术后PVR的显著危险因素是术前视力差和手术期间大量的激光光凝(p<0.05)。所有眼睛、黄斑脱离的眼睛、人工晶状体眼以及晶状体眼的视力均显著提高。黄斑在位眼睛的视力没有显著变化。6例患者发生了高眼压,另外6例出现了视网膜前膜。3例患者报告有视野缺损。94例晶状体眼中的64例(68%)出现晶状体混浊加重。
量身定制的玻璃体切除手术方案适用于所有类型的RRD。晶状体眼中晶状体混浊加重很常见,但晶状体眼和人工晶状体眼的视力均有显著改善。术后PVR的发生与激光治疗的范围有关,表明该方案未来可能会进一步优化。