Azad Raj Vardhan, Chanana Bhuvan, Sharma Yog Raj, Vohra Rajpal
Vitreo-Retina Services, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Acta Ophthalmol Scand. 2007 Aug;85(5):540-5. doi: 10.1111/j.1600-0420.2007.00888.x. Epub 2007 Mar 9.
This study aimed to compare the results of primary vitrectomy and conventional scleral buckling procedures (conventional retinal detachment surgery) in phakic rhegmatogenous retinal detachment (RRD).
We carried out a randomized, prospective, clinical controlled trial of 61 consecutive phakic eyes with primary RRD, not complicated by proliferative vitreoretinopathy >or= grade C. Subjects were randomized to either scleral buckling (group 1) or pars plana vitrectomy (group 2).
At 6 months follow-up, the primary reattachment rate was 80% (24/30 cases) in group 2 and 80.6% (25/31 cases) in group 1; the difference between the two groups was not statistically significant (p = 0.213). Best corrected visual acuity improved significantly from a preoperative median of 1.78 (1/60) (mean 1.73 +/- 0.91, range 0.3-3) to a median of 0.6 (6/24) (mean 0.689 +/- 0.35, range 0.18-1.48) in group 2 and from a preoperative median of 1.48 (2/60) (mean 1.43 +/- 0.92, range 0-3) to a median of 0.6 (6/24) (mean 0.608 +/- 0.36, range 0-1.78) in group 1; the difference between the two groups was not statistically significant (p = 0.376). Cataract developed in five cases (17%) in the vitrectomy group (group 2), with a statistically significant difference of p = 0.018.
Although primary vitrectomy can achieve anatomical and functional success rates comparable with those achieved by scleral buckling in uncomplicated forms of phakic RRD, the major drawback of the procedure is the high incidence of postoperative cataract formation. Moreover, visual rehabilitation takes place earlier with scleral buckling than with vitrectomy. Scleral buckling should thus be used as the primary surgical modality in the treatment of uncomplicated RRD where the media are sufficiently clear.
本研究旨在比较在有晶状体孔源性视网膜脱离(RRD)中,一期玻璃体切除术与传统巩膜扣带术(传统视网膜脱离手术)的效果。
我们对61例连续的、未合并增殖性玻璃体视网膜病变≥C级的有晶状体原发性RRD患者进行了一项随机、前瞻性临床对照试验。受试者被随机分为巩膜扣带术组(第1组)或玻璃体切除术组(第2组)。
在6个月的随访中,第2组的一期复位率为80%(24/30例),第1组为80.6%(25/31例);两组之间的差异无统计学意义(p = 0.213)。最佳矫正视力从第2组术前中位数1.78(1/60)(平均1.73±0.91,范围0.3 - 3)显著提高到中位数0.6(6/24)(平均0.689±0.35,范围0.18 - 1.48),第1组从术前中位数1.48(2/60)(平均1.43±0.92,范围0 - 3)提高到中位数0.6(6/24)(平均0.608±0.36,范围0 - 1.78);两组之间的差异无统计学意义(p = 0.376)。玻璃体切除术组(第2组)有5例(17%)发生白内障,差异有统计学意义,p = 0.018。
尽管一期玻璃体切除术在未合并复杂情况的有晶状体RRD中能取得与巩膜扣带术相当的解剖和功能成功率,但该手术的主要缺点是术后白内障形成的发生率高。此外,巩膜扣带术比玻璃体切除术能更早实现视力恢复。因此,在治疗未合并复杂情况且屈光间质足够清晰的RRD时,巩膜扣带术应作为主要的手术方式。