原发性头痛中的血小板甘氨酸、谷氨酸和天冬氨酸

Platelet glycine, glutamate and aspartate in primary headache.

作者信息

D'Andrea G, Cananzi A R, Joseph R, Morra M, Zamberlan F, Ferro Milone F, Grunfeld S, Welch K M

机构信息

Department of Neurology, San Bortolo Hospital, Vicenza, Italy.

出版信息

Cephalalgia. 1991 Sep;11(4):197-200. doi: 10.1046/j.1468-2982.1991.1104197.x.

DOI:10.1046/j.1468-2982.1991.1104197.x

PMID:1683816

Abstract

Platelet levels of glutamic and aspartic acid and glycine were measured in patients with migraine with aura, migraine without aura, tension headache and cluster headache. High levels of these amino acids were found in patients with migraine with aura compared to normal subjects and other headache groups. During headache, glutamate levels further increased in migraine with aura patients. These findings may have relevance to the neurological symptoms of migraine with aura.

摘要

对有先兆偏头痛、无先兆偏头痛、紧张性头痛和丛集性头痛患者的血小板谷氨酸、天冬氨酸和甘氨酸水平进行了测量。与正常受试者和其他头痛组相比，有先兆偏头痛患者中这些氨基酸水平较高。在头痛发作期间，有先兆偏头痛患者的谷氨酸水平进一步升高。这些发现可能与有先兆偏头痛的神经症状有关。