Ovesen L, Hannibal J, Sørensen M, Allingstrup L
Department of Medicine C, Division of Oncology Bispebjerg University Hospital, Bispebjerg Bakke, 2400 Copenhagen NV, Denmark.
Clin Nutr. 1991 Dec;10(6):336-41. doi: 10.1016/0261-5614(91)90063-i.
Nutritional status and energy and protein intake were studied in 52 patients with cancer of the breast, ovary or lung before, after 1, and after 3 cycles of aggressive chemotherapy. Pre-treatment intakes were somewhat lower than recommended and did not change after 3 cycles of chemotherapy, neither did nutritional status. Many patients had eating-related complaints, but these complaints did not increase significantly with chemotherapeutic treatment. In 31 patients electrical taste detection thresholds and chemical smell detection thresholds were measured before and after 3 cycles of chemotherapy. Changes in thresholds had no relation to changes in energy and protein intake. Perceived taste and smell changes were not reflected in chemosensory threshold values.
对52例乳腺癌、卵巢癌或肺癌患者在进行积极化疗前、化疗1个周期后及化疗3个周期后进行了营养状况、能量和蛋白质摄入量的研究。治疗前的摄入量略低于推荐量,化疗3个周期后没有变化,营养状况也没有改变。许多患者有与饮食相关的主诉,但这些主诉并未随着化疗治疗而显著增加。对31例患者在化疗3个周期前后测量了电味觉检测阈值和化学嗅觉检测阈值。阈值的变化与能量和蛋白质摄入量的变化无关。味觉和嗅觉的感知变化并未反映在化学感觉阈值上。