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本文引用的文献

1
Differential expression of a BMP4 reporter allele in anterior fungiform versus posterior circumvallate taste buds of mice.在小鼠的前菌状和后环状味蕾中,BMP4 报告基因等位基因的差异表达。
BMC Neurosci. 2010 Oct 13;11:129. doi: 10.1186/1471-2202-11-129.
2
The cells and peripheral representation of sodium taste in mice.小鼠的钠味觉的细胞和外周表现。
Nature. 2010 Mar 11;464(7286):297-301. doi: 10.1038/nature08783. Epub 2010 Jan 27.
3
Epidermal stem cell diversity and quiescence.表皮干细胞的多样性和静止状态。
EMBO Mol Med. 2009 Aug;1(5):260-7. doi: 10.1002/emmm.200900033.
4
Sox2 and Oct-3/4: a versatile pair of master regulators that orchestrate the self-renewal and pluripotency of embryonic stem cells.Sox2 和 Oct-3/4:一对万能的主调控因子,协调胚胎干细胞的自我更新和多能性。
Wiley Interdiscip Rev Syst Biol Med. 2009 Sep-Oct;1(2):228-236. doi: 10.1002/wsbm.12.
5
Gustatory alteration evaluation in patients with chronic otitis media.慢性中耳炎患者味觉改变的评估。
Braz J Otorhinolaryngol. 2009 Jul-Aug;75(4):550-5. doi: 10.1016/s1808-8694(15)30495-x.
6
Inward rectifier channel, ROMK, is localized to the apical tips of glial-like cells in mouse taste buds.内向整流通道ROMK定位于小鼠味蕾中胶质样细胞的顶端。
J Comp Neurol. 2009 Nov 1;517(1):1-14. doi: 10.1002/cne.22152.
7
Reduction of type II taste cells correlates with taste dysfunction after X-ray irradiation in mice.X 射线照射后,Ⅱ型味觉细胞减少与小鼠味觉功能障碍相关。
J Oral Pathol Med. 2010 Mar;39(3):212-8. doi: 10.1111/j.1600-0714.2009.00823.x. Epub 2009 Aug 23.
8
Inflammation and taste disorders: mechanisms in taste buds.炎症与味觉障碍:味蕾中的机制
Ann N Y Acad Sci. 2009 Jul;1170:596-603. doi: 10.1111/j.1749-6632.2009.04480.x.
9
Psychophysical effects of nasal and oral inflammation.鼻腔和口腔炎症的心理生理效应。
Ann N Y Acad Sci. 2009 Jul;1170(1):585-9. doi: 10.1111/j.1749-6632.2009.04370.x.
10
In vivo fate tracing studies of mammalian taste cell progenitors.哺乳动物味觉细胞祖细胞的体内命运追踪研究。
Ann N Y Acad Sci. 2009 Jul;1170:34-8. doi: 10.1111/j.1749-6632.2009.04371.x.

味蕾再生与味觉祖细胞的探寻

Taste bud regeneration and the search for taste progenitor cells.

作者信息

Miura H, Barlow L A

机构信息

Dept of Oral Physiology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.

出版信息

Arch Ital Biol. 2010 Jun;148(2):107-18.

PMID:20830973
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3545678/
Abstract

While the taste periphery has been studied for over a century, we are only beginning to understand how this important sensory system is maintained throughout adult life. With the advent of molecular genetics in rodent models, and the upswing in translational approaches that impact human patients, we expect the field will make significant advances in the near future.

摘要

虽然味觉外周已经被研究了一个多世纪,但我们才刚刚开始了解这个重要的感觉系统在成年期是如何维持的。随着啮齿动物模型中分子遗传学的出现,以及影响人类患者的转化方法的兴起,我们预计该领域在不久的将来将取得重大进展。