Boztepe Gonca, Akinci Hande, Sahin Sedef, Karaduman Aysen, Evans Sibel Ersoy, Erkin Gül, Atakan Nilgün, Akan Tülin, Kölemen Fikret
Hacettepe University Faculty of Medicine, Department of Dermatology, Sihhiye, 06100, Ankara, Turkey.
J Am Acad Dermatol. 2006 Aug;55(2):269-71. doi: 10.1016/j.jaad.2006.04.019.
Our aim was to compare 20% with 10% to 5% incremental regimens in narrowband UVB phototherapy.
The study included patients with psoriasis (N = 191) with Fitzpatrick skin phototypes II and III.
Occurrence of erythema as well as maximum and cumulative doses were higher with 20% escalations, whereas response rates and time to response did not significantly differ.
The study was limited by its retrospective nature.
A 5% or 10% incremental regimen may have similar therapeutic efficacy.
我们的目的是比较窄谱中波紫外线光疗中20%递增方案与10%至5%递增方案的效果。
该研究纳入了191例患有银屑病、皮肤菲茨帕特里克分型为II型和III型的患者。
20%递增方案的红斑发生率、最大剂量和累积剂量更高，而有效率和起效时间无显著差异。
该研究受其回顾性性质的限制。
5%或10%的递增方案可能具有相似的治疗效果。
