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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

School of Neurosciences, University of Newcastle upon Tyne, UK.

Int Clin Psychopharmacol. 1991 Jul;6 Suppl 1:83-9.

The most important recent research leading to future developments in the understanding and treatment of chronic depression are the clinical and epidemiological approaches. 2. The central role of 5HT in depression is emphasized and it seems likely that the maintenance of adequate 5HT neurotransmission is required for the treatment of chronic depression. 3. The role of organic changes in chronic depression must be further explored. 4. The development of novel antidepressants, particularly prophylactic ones, is the most likely way to produce major clinical benefits for this disabled group.

近期对理解和治疗慢性抑郁症具有引领未来发展意义的最重要研究是临床和流行病学方法。2. 强调了5-羟色胺（5HT）在抑郁症中的核心作用，并且维持足够的5HT神经传递似乎是治疗慢性抑郁症所必需的。3. 必须进一步探究慢性抑郁症中器质性变化的作用。4. 开发新型抗抑郁药，尤其是预防性抗抑郁药，是最有可能为这一残疾群体带来重大临床益处的途径。

School of Neurosciences, University of Newcastle upon Tyne, UK.

Int Clin Psychopharmacol. 1991 Jul;6 Suppl 1:83-9.

The most important recent research leading to future developments in the understanding and treatment of chronic depression are the clinical and epidemiological approaches. 2. The central role of 5HT in depression is emphasized and it seems likely that the maintenance of adequate 5HT neurotransmission is required for the treatment of chronic depression. 3. The role of organic changes in chronic depression must be further explored. 4. The development of novel antidepressants, particularly prophylactic ones, is the most likely way to produce major clinical benefits for this disabled group.

近期对理解和治疗慢性抑郁症具有引领未来发展意义的最重要研究是临床和流行病学方法。2. 强调了5-羟色胺（5HT）在抑郁症中的核心作用，并且维持足够的5HT神经传递似乎是治疗慢性抑郁症所必需的。3. 必须进一步探究慢性抑郁症中器质性变化的作用。4. 开发新型抗抑郁药，尤其是预防性抗抑郁药，是最有可能为这一残疾群体带来重大临床益处的途径。