Richelson E
Department of Psychiatry, Mayo Clinic Jacksonville, Florida.
Psychiatr Clin North Am. 1993 Sep;16(3):461-78.
This article presents information needed by the clinician to diagnose and treat acute depression. The emphasis is on the pharmacologic treatment of depression. Both clinical and preclinical pharmacology of antidepressants are reviewed. The data presented will help the clinician make a rational choice of antidepressant for his or her patient. In particular, these data will help the clinician avoid or minimize certain adverse effects and drug-drug interactions. Guidelines for treating depression as well as strategies for treating the refractory patient are presented.
本文提供了临床医生诊断和治疗急性抑郁症所需的信息。重点是抑郁症的药物治疗。本文回顾了抗抑郁药的临床药理学和临床前药理学。所提供的数据将帮助临床医生为其患者合理选择抗抑郁药。特别是，这些数据将帮助临床医生避免或尽量减少某些不良反应和药物相互作用。本文还介绍了抑郁症的治疗指南以及治疗难治性患者的策略。
