Babadzhan V D, Koval' S N, Zeĭnalov F M, Masliaeva L V
Vrach Delo. 1991 Sep(9):44-6.
Natriuretic hormone is a digoxin-like substance that inhibits Na-K-ATPase, membraneous sodium pump, leads to storage of sodium in the cells, increases their tone which plays a key role in the increase of peripheral resistance of the blood vessels and progression of hypertensive disease. Results indicate that the level of natriuretic hormone was increased at all stages of hypertensive disease, positively correlated with aldosterone and kallikrein and negatively--with the plasma renin activity that confirms its pressor action.
利钠激素是一种类地高辛物质，它抑制钠钾ATP酶，即细胞膜钠泵，导致钠在细胞内蓄积，增加细胞张力，这在血管外周阻力增加和高血压疾病进展中起关键作用。结果表明，在高血压疾病的所有阶段，利钠激素水平均升高，与醛固酮和激肽释放酶呈正相关，与血浆肾素活性呈负相关，这证实了其升压作用。
