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利用宫内磁共振成像技术对胎儿脊柱进行成像:诊断准确性及对治疗的影响。

Imaging the fetal spine using in utero MR: diagnostic accuracy and impact on management.

作者信息

Griffiths Paul D, Widjaja Elysa, Paley Martyn N J, Whitby Elspeth H

机构信息

Academic Unit of Radiology, Royal Hallamshire Hospital, University of Sheffield, Glossop Road, Sheffield, S10 2JF, UK.

出版信息

Pediatr Radiol. 2006 Sep;36(9):927-33. doi: 10.1007/s00247-006-0234-y. Epub 2006 Jul 18.

DOI:10.1007/s00247-006-0234-y
PMID:16847599
Abstract

BACKGROUND

In-utero MR imaging (iuMR) has entered the clinical arena during the last decade. It is used mainly for imaging fetal brain abnormalities.

OBJECTIVE

To report our experience of imaging the fetal spine and spinal cord in fetuses with known or suspected abnormalities diagnosed on US imaging.

MATERIALS AND METHODS

Prospective imaging and retrospective analysis of the possible impact on management of 50 consecutive fetuses with spinal abnormalities detected by antenatal US imaging.

RESULTS

In 40 (80%) of 50 fetuses, iuMR and US imaging were in complete agreement. In the other 10 fetuses (20%), iuMR provided additional information or changed the diagnosis, including 8 fetuses where the iuMR could find no abnormality and was found to be correct by later follow-up.

CONCLUSION

IuMR is useful in fetuses with a suspected spinal abnormality. The clinical impact of iuMR may be numerically less than with brain abnormalities, but is still sufficient to warrant its use, especially if there is any uncertainty about the US imaging, and particularly as a relatively high proportion of diagnoses on US imaging are false-positives.

摘要

背景

胎儿磁共振成像(iuMR)在过去十年已进入临床领域。它主要用于对胎儿脑异常进行成像。

目的

报告我们对超声成像诊断为已知或疑似异常的胎儿脊柱和脊髓进行成像的经验。

材料与方法

对产前超声成像检测出的50例连续脊柱异常胎儿进行前瞻性成像,并对其对治疗的可能影响进行回顾性分析。

结果

50例胎儿中的40例(80%),iuMR与超声成像完全一致。在其他10例胎儿(20%)中,iuMR提供了额外信息或改变了诊断结果,其中8例iuMR未发现异常,后来的随访证实其诊断正确。

结论

iuMR对疑似脊柱异常的胎儿有用。iuMR对临床的影响在数量上可能比脑异常情况少,但仍足以保证其应用,特别是当超声成像存在任何不确定性时,尤其是因为超声成像的诊断中有相当比例为假阳性。

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Comparison of ultrasound and magnetic resonance imaging in 100 singleton pregnancies with suspected brain abnormalities.100例疑似脑异常单胎妊娠中超声与磁共振成像的比较
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Differential growth rates of the cerebellum and posterior fossa assessed by post mortem magnetic resonance imaging of the fetus: implications for the pathogenesis of the chiari 2 deformity.通过胎儿尸检磁共振成像评估小脑和后颅窝的差异生长率:对Chiari 2畸形发病机制的影响。
Use of magnetic resonance imaging in the diagnosis of fetal vertebral abnormalities in utero: a single-center retrospective cohort study.
磁共振成像在产前诊断胎儿脊柱异常中的应用:一项单中心回顾性队列研究
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Antenatal management of fetal neurosurgical diseases.胎儿神经外科疾病的产前管理
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Magnetic resonance imaging in the prenatal diagnosis of neural tube defects.磁共振成像在神经管缺陷产前诊断中的应用。
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