Thiounn N
Clinique Urologique, Hôpital Cochin, Paris.
J Urol (Paris). 1991;97(4-5):189-94.
Intracavernous injections have been used for about 10 years for the diagnosis and treatment of erectile insufficiencies. This development has been justified by a better knowledge of the physiology of erection and by the recent use of prostaglandin E1. We have reviewed the information provided by the literature (major journals of urology, medicine and physiology), as well as our experience of erectile insufficiency. Diagnostic intracavernous injections allows ruling out vascular or cavernous causes when the injection is followed by a stiff erection within 10 minutes and for more than 20 minutes, whatever the vasoactive agent used. All the causes of erectile insufficiency can be treated with intracavernous injections if the induced erection allows penetration. Prostaglandin E1 provides the highest response rate with fewer adverse effects, but it is not commonly available at present.
海绵体内注射用于勃起功能不全的诊断和治疗已有约10年。对勃起生理学的更深入了解以及近期前列腺素E1的应用使这一进展具有合理性。我们回顾了文献(泌尿外科、医学和生理学的主要期刊)提供的信息以及我们在勃起功能不全方面的经验。诊断性海绵体内注射如果在注射后10分钟内出现坚挺勃起且持续超过20分钟,无论使用何种血管活性药物,都可排除血管性或海绵体性病因。如果诱导勃起能实现性交,所有勃起功能不全的病因都可用海绵体内注射治疗。前列腺素E1的有效率最高且不良反应较少,但目前并不常用。