Cosgriff T M, Lewis R M
Hematology-Oncology Service, Fitzsimons Army Medical Center Aurora, Colorado.
Kidney Int Suppl. 1991 Dec;35:S72-9.
Hemorrhagic fever with renal syndrome (HFRS) is a dramatic illness characterized by fever, and variable degrees of circulatory failure, hemorrhage, and renal insufficiency. Hantaviruses are the cause of this syndrome. In its severe form, it is associated with significant mortality. Vascular dysfunction is the key physiologic derangement in this disorder. There is a growing body of evidence that suggests that immune mechanisms account for this derangement.
肾综合征出血热（HFRS）是一种以发热、不同程度的循环衰竭、出血和肾功能不全为特征的严重疾病。汉坦病毒是该综合征的病因。在其严重形式下，它与显著的死亡率相关。血管功能障碍是这种疾病的关键生理紊乱。越来越多的证据表明，免疫机制是导致这种紊乱的原因。
