Georgieva Radostina, Moya Sergio E, Bäumler Hans, Möhwald Helmuth, Donath Edwin
Max Planck Institute of Colloids and Interfaces, Am Mühlenberg 1, 14476 Golm/Potsdam, Germany.
J Phys Chem B. 2005 Sep 29;109(38):18025-30. doi: 10.1021/jp0521407.
The effect of cholesterol on the formation and properties of bilayer lipid membranes deposited on polyelectrolyte multilayered capsules was studied. The permeability of lipid/cholesterol coated capsules for NaCl was derived from osmotic response experiments and ranged from 1.45 x 10(-8) to 2.9 x 10(-8) m.s(-1), which corresponds to a lipid layer conductivity of (0.7-1.4) x 10(-8) S.m(-1). These conductivity values were in good agreement with the value of 0.8 x 10(-8) S.m(-1) obtained by electrorotation and were by 3 orders of magnitude lower than those found earlier for lipid layers on polyelectrolyte capsules in the absence of cholesterol.
研究了胆固醇对沉积在聚电解质多层胶囊上的双层脂质膜的形成及性质的影响。脂质/胆固醇包被的胶囊对氯化钠的渗透性通过渗透响应实验得出，范围为1.45×10⁻⁸至2.9×10⁻⁸m·s⁻¹，这对应于脂质层电导率为(0.7 - 1.4)×10⁻⁸S·m⁻¹。这些电导率值与通过电旋转获得的0.8×10⁻⁸S·m⁻¹的值高度吻合，并且比早期在没有胆固醇的情况下聚电解质胶囊上的脂质层所发现的值低3个数量级。
