Hu Chenguo, Zhang Yiyi, Bao Gang, Zhang Yuelan, Liu Meilin, Wang Zhong Lin
Department of Applied Physics, Chongqing University, Chongqing 400044, China.
J Phys Chem B. 2005 Nov 3;109(43):20072-6. doi: 10.1021/jp0550457.
Single-walled carbon nanotubes (SWNTs) were effectively dispersed and functionalized by wrapping with single-stranded DNA (ssDNA). The ssDNA-SWNTs attach strongly on glass substrate and easily form a uniform film, making it possible for electrochemical analysis and sensing. The film was fabricated into a working electrode, which exhibited good electrochemical voltammetric properties, such as flat and wide potential window, well-defined quasi-reversible voltammetric responses, and quick electron transfer for a Fe(CN)6(3-)/Fe(CN)6(4) system, indicating that the ssDNA-SWNTs film should be a good analytical electrode for electrochemical detection or sensing. This was demonstrated by highly selective and sensitive detection of a low concentration of dopamine in the presence of excess ascorbic acid.
单壁碳纳米管（SWNTs）通过与单链DNA（ssDNA）包裹而有效地分散并功能化。ssDNA-SWNTs牢固地附着在玻璃基板上，并易于形成均匀的薄膜，这使得电化学分析和传感成为可能。该薄膜被制成工作电极，表现出良好的电化学伏安特性，如平坦且宽的电位窗口、明确的准可逆伏安响应以及对于Fe(CN)6(3-)/Fe(CN)6(4)体系的快速电子转移，表明ssDNA-SWNTs薄膜应该是用于电化学检测或传感的良好分析电极。在过量抗坏血酸存在的情况下对低浓度多巴胺进行高选择性和高灵敏度检测证明了这一点。
