Sterrett G F, Heenan P J, Wyche P, Papadimitriou J M
Pathology. 1975 Apr;7(2):139-47. doi: 10.3109/00313027509092710.
A case of malakoplakia of the prostate is presented. Electron microscopic appearances support the origin of the Michaelis-Gutmann bodies from phagolysosomes in the histiocytes characteristic of the lesion. Biochemical analysis revealed the presence of muramic acid in the prostate with malakoplakia. This amino sugar is characteristic of bacterial cell walls and despite the absence of demonstrable bacteria in the affected tissues indicates the involvement of bacteria in the disease process.
本文报告一例前列腺软斑病。电子显微镜观察结果支持迈-古二氏小体起源于病变特征性组织细胞中的吞噬溶酶体。生化分析显示，患软斑病的前列腺中存在胞壁酸。这种氨基糖是细菌细胞壁的特征物质，尽管在受累组织中未发现可证实的细菌，但表明细菌参与了疾病过程。
