Bode Helge B, Ring Michael W, Kaiser Dale, David Anna C, Kroppenstedt Reiner M, Schwär Gertrud
Institut für Pharmazeutische Biotechnologie, Universität des Saarlandes, P.O. Box 151150, 66041 Saarbrücken, Germany.
J Bacteriol. 2006 Aug;188(15):5632-4. doi: 10.1128/JB.00438-06.
Inactivation of the MXAN_0853 gene blocked the production in Myxococcus xanthus of straight-chain fatty acids which otherwise represent 30% of total fatty acids. Despite this drastic change in the fatty acid profile, no change in phenotype could be observed, which contrasts with previous interpretations of the role of straight-chain fatty acids in the organism's development.
MXAN_0853基因的失活阻止了黄色粘球菌中直链脂肪酸的产生,否则直链脂肪酸占总脂肪酸的30%。尽管脂肪酸谱发生了如此剧烈的变化,但未观察到表型变化,这与之前对直链脂肪酸在该生物体发育中作用的解释形成了对比。