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手辅助腹腔镜脾切除术及上腹部胃去血管化术治疗胃静脉曲张

Hand-assisted laparoscopic splenectomy and devascularization of the upper stomach in the management of gastric varices.

作者信息

Yamamoto Joji, Nagai Motoki, Smith Barry, Tamaki Satoshi, Kubota Tadao, Sasaki Ken, Ohmori Toshihiro, Maeda Kiyotaka

机构信息

Department of Surgery, Chibanishi General Hospital, Chiba, Japan.

出版信息

World J Surg. 2006 Aug;30(8):1520-5. doi: 10.1007/s00268-005-0243-2.

Abstract

BACKGROUND

Bleeding from esophagogastric varices is the major cause of death in patients with portal hypertension. Although esophageal varices can be treated with endoscopic procedures, the treatment for gastric varices is still controversial. The aim of this study was to describe a surgical technique and our preliminary results of hand-assisted laparoscopic Hassab's procedure.

METHODS

Between February 2002 and May 2005, we performed 7 cases of gastric varices with this type of operation. The patients included 4 men and 3 women who ranged in age from 23 to 74 years (underlying liver disease: 5 case of liver cirrhosis, 1 case of polycystic disease, 1 case of extrahepatic portal vein obstruction). After splenctomy was performed, we devascularized the vessels of the upper stomach and the esophagus 5 cm away from the esophago-cardia junction.

RESULTS

The operative time ranged from 132 to 290 minutes. Intraoperative blood loss was estimated to be from 50 ml to 475 ml. The weight of removed spleen ranged from 110 g to 800 g. During the follow-up period, all gastric varices disappeared and no bleeding from varicose veins was observed. All patients had hypersplenism with thrombocytopenia before surgery (mean: 11.1+/-7.4x10(4)/ml), which was improved postoperatively (mean: 30.8+/-19.0x10(4)/ml). This data were statistically significant (P=0.033). One patient died of aspiration pneumonia related to postoperative pyloric stricture.

CONCLUSIONS

Although there is no agreement concerning the best treatment of gastric varices, the hand-assisted laparoscopic Hassab's operation is a safe, moderately invasive method, and its outcome appears to be equal to that of other open procedures.

摘要

背景

食管胃静脉曲张出血是门静脉高压患者的主要死因。尽管食管静脉曲张可通过内镜手术治疗,但胃静脉曲张的治疗仍存在争议。本研究的目的是描述一种手术技术以及我们手辅助腹腔镜下哈萨布手术的初步结果。

方法

2002年2月至2005年5月期间,我们用这种手术方式治疗了7例胃静脉曲张患者。患者包括4名男性和3名女性,年龄在23至74岁之间(基础肝病:5例肝硬化,1例多囊病,1例肝外门静脉阻塞)。脾切除术后,我们对胃上部和距食管贲门交界处5厘米处的食管血管进行去血管化处理。

结果

手术时间为132至290分钟。术中估计失血量为50至475毫升。切除脾脏的重量为110至800克。随访期间,所有胃静脉曲张均消失,未观察到静脉曲张出血。所有患者术前均有脾功能亢进伴血小板减少(平均:11.1±7.4×10⁴/ml),术后有所改善(平均:30.8±19.0×10⁴/ml)。该数据具有统计学意义(P = 0.033)。1例患者死于与术后幽门狭窄相关的吸入性肺炎。

结论

尽管对于胃静脉曲张的最佳治疗尚无共识,但手辅助腹腔镜下哈萨布手术是一种安全、微创性适中的方法,其结果似乎与其他开放手术相当。

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