Zhang Xiao-Hong, Wu Wei-Wei, Tang Jian-Xin, Qian Guang-Li, Zhang Xiao-Ming
Panyu Division of Guangzhou Public Security Bureau, Guangzhou 511400, China.
Fa Yi Xue Za Zhi. 2006 Jun;22(3):210-2, 216.
To abtain the genetic polymorphisms data of eleven Y-chromosome STR loci in Yunnan Han population, and to evaluate its forensic application values, which will provide the base data for forensic application.
DYS391, DYS389 I, DYS439, DYS389 II, DYS438, DYS437, DYS19, DYS392, DYS393, DYS390 and DYS385a/b loci were amplified by using Powerplex Y PCR amplification Kit and were analyzed by 310 genetic analyzer. 201 unrelated male individuals of Han population in Yunnan were investigated to determine the distributions of allele frequencies and haplotypes.
3, 5, 6, 8, 5, 4, 5, 8, 4, 7 alleles were found across the Y-STR loci except DYS38556 haplotypes were found across DYS385a/b locus. The minimum GD value was 0.4273 (DYS438), and the maximum was 0.9747 (DYS385a/b). 175 haplotypes were found, of which 154 were unique, 16 were found in 2 individuals, 5 were found in 3 individuals, and the observed haplotypes diversity value was 0.9984.
The 11 Y-STR loci are highly polymorphic and are suitable for forensic personal identification and paternity testing in Yunnan Han population.
获取云南汉族人群11个Y染色体STR基因座的遗传多态性数据，评估其法医学应用价值，为法医学应用提供基础数据。
采用Powerplex Y PCR扩增试剂盒对DYS391、DYS389 I、DYS439、DYS389 II、DYS438、DYS437、DYS19、DYS392、DYS393、DYS390和DYS385a/b基因座进行扩增，并用310遗传分析仪进行分析。调查云南汉族201名无血缘关系男性个体，确定等位基因频率和单倍型分布。
除DYS385a/b基因座发现56种单倍型外，各Y-STR基因座分别发现3、5、6、8、5、4、5、8、4、7个等位基因。最小GD值为0.4273（DYS438），最大为0.9747（DYS385a/b）。共发现175种单倍型，其中154种为独特单倍型，16种在2个个体中出现，5种在3个个体中出现，观察到的单倍型多样性值为0.9984。
11个Y-STR基因座具有高度多态性，适用于云南汉族人群的法医学个体识别和亲子鉴定。
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