中国山东省汉族人群中17个Y染色体短串联重复序列（Y-STR）单倍型的基因多态性。
Genetic polymorphisms of 17 Y-STRs haplotypes in Chinese Han population residing in Shandong province of China.
作者信息
Yan Jiangwei, Tang Hui, Liu Yacheng, Jing Yuting, Jiao Zhangping, Zhang Qingxia, Gao Junwei, Shang Leipeng, Guo Hua, Yu Jun
机构信息
Graduate University of Chinese Academy of Sciences, Beijing 100049, China.
出版信息
Leg Med (Tokyo). 2007 Jul;9(4):196-202. doi: 10.1016/j.legalmed.2006.11.016. Epub 2007 Feb 1.
We have co-amplified (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385a,b, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, and Y GATA H4) in a single PCR using the AmpFLSTR Yfiler PCR Amplification system. Allelic frequency distribution and haplotype diversity of 17 Y-chromosomal STR from a sample of 131 unrelated individuals of Chinese Han population living in Shandong province of China were obtained. A total of 129 haplotypes were observed in the 131 individuals studied, of which 127 were unique and two were found in two individuals. The gene diversity values ranged from 0.3560 (DYS391) to 0.9675 (DYS385a,b), The overall haplotype diversity for the 17 Y-STR loci was 0.9998, and the discrimination capacity was 0.9695. These results are compared with those observed in worldwide populations at both the locus and the haplotype level.
我们使用AmpFLSTR Yfiler PCR扩增系统在一次聚合酶链式反应（PCR）中共同扩增了（DYS19、DYS389I、DYS389II、DYS390、DYS391、DYS392、DYS393、DYS385a,b、DYS437、DYS438、DYS439、DYS448、DYS456、DYS458、DYS635以及Y GATA H4）。我们获得了来自中国山东省131名无亲缘关系的汉族人群样本中17个Y染色体短串联重复序列（STR）的等位基因频率分布和单倍型多样性。在所研究的131名个体中总共观察到129种单倍型，其中127种是独特的，另外两种在两名个体中出现。基因多样性值范围从0.3560（DYS391）到0.9675（DYS385a,b），17个Y-STR位点的总体单倍型多样性为0.9998，鉴别能力为0.9695。这些结果在基因座和单倍型水平上与在全球人群中观察到的结果进行了比较。
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