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威尔逊病中的肝细胞癌:儿童期的一种罕见关联。

Hepatocellular carcinoma in Wilson's disease: a rare association in childhood.

作者信息

Savas Nurten, Canan Oguz, Ozcay Figen, Bilezikci Banu, Karakayali Hamdi, Yilmaz Ugur, Haberal Mehmet

机构信息

Department of Gastroenterology, Baskent University Faculty of Medicine, Ankara, Turkey.

出版信息

Pediatr Transplant. 2006 Aug;10(5):639-43. doi: 10.1111/j.1399-3046.2006.00562.x.

Abstract

Wilson's disease is a hereditary disorder of copper metabolism that results in the accumulation of copper in the body, primarily in the liver, brain, and cornea. Hepatocellular carcinoma, in contrast to other causes of cirrhosis, is seldom associated with Wilson's disease. We present a 12-yr-old boy with Wilson's disease in whom hepatocellular carcinoma was incidentally diagnosed in the pathologic specimen examined after liver transplantation.

摘要

威尔逊病是一种铜代谢的遗传性疾病,会导致铜在体内蓄积,主要在肝脏、大脑和角膜。与其他肝硬化病因不同,肝细胞癌很少与威尔逊病相关。我们报告一名患有威尔逊病的12岁男孩,在肝移植后检查的病理标本中意外诊断出肝细胞癌。

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