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纤维肌痛综合征的心理疼痛治疗:操作性行为治疗和认知行为治疗的疗效

Psychological pain treatment in fibromyalgia syndrome: efficacy of operant behavioural and cognitive behavioural treatments.

作者信息

Thieme Kati, Flor Herta, Turk Dennis C

机构信息

Department of Clinical and Cognitive Neuroscience, University of Heidelberg, Central Institute of Mental Health, J5, 68169 Mannheim, Germany.

出版信息

Arthritis Res Ther. 2006;8(4):R121. doi: 10.1186/ar2010.

Abstract

The present study focused on the evaluation of the effects of operant behavioural (OBT) and cognitive behavioural (CBT) treatments for fibromyalgia syndrome (FMS). One hundred and twenty-five patients who fulfilled the American College of Rheumatology criteria for FMS were randomly assigned to OBT (n = 43), CBT (n = 42), or an attention-placebo (AP) treatment (n = 40) that consisted of discussions of FMS-related problems. Assessments of physical functioning, pain, affective distress, and cognitive and behavioural variables were performed pre-treatment and post-treatment as well as 6 and 12 months post-treatment. Patients receiving the OBT or CBT reported a significant reduction in pain intensity post-treatment (all Fs > 3.89, all Ps < 0.01). In addition, the CBT group reported statistically significant improvements in cognitive (all Fs > 7.95, all P < 0.01) and affective variables (all Fs > 2.99, all Ps < 0.02), and the OBT group demonstrated statistically significant improvements in physical functioning and behavioural variables (all Fs > 5.99, all Ps < 0.001) compared with AP. The AP group reported no significant improvement but actually deterioration in the outcome variables. The post-treatment effects for the OBT and CBT groups were maintained at both the 6- and 12-month follow-ups. These results suggest that both OBT and CBT are effective in treating patients with FMS with some differences in the outcome measures specifically targeted by the individual treatments compared with an unstructured discussion group. The AP group showed that unstructured discussion of FMS-related problems may be detrimental.

摘要

本研究聚焦于评估操作性行为疗法(OBT)和认知行为疗法(CBT)对纤维肌痛综合征(FMS)的治疗效果。125名符合美国风湿病学会FMS标准的患者被随机分配至OBT组(n = 43)、CBT组(n = 42)或注意力安慰剂(AP)治疗组(n = 40),AP治疗组包括对FMS相关问题的讨论。在治疗前、治疗后以及治疗后6个月和12个月对身体功能、疼痛、情感困扰以及认知和行为变量进行评估。接受OBT或CBT治疗的患者在治疗后报告疼痛强度显著降低(所有F值> 3.89,所有P值< 0.01)。此外,与AP组相比,CBT组在认知变量(所有F值> 7.95,所有P < 0.01)和情感变量方面有统计学意义的显著改善(所有F值> 2.99,所有P值< 0.02),OBT组在身体功能和行为变量方面有统计学意义的显著改善(所有F值> 5.99,所有P值< 0.001)。AP组报告结果变量无显著改善,实际上还有恶化。OBT组和CBT组的治疗后效果在6个月和12个月的随访中均得以维持。这些结果表明,与非结构化讨论组相比,OBT和CBT在治疗FMS患者方面均有效,且在个体治疗所针对的结果测量方面存在一些差异。AP组表明,对FMS相关问题进行非结构化讨论可能有害。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdff/1779398/637ea0ac2866/ar2010-1.jpg

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