Xu Ping, Yu Bo, Li Fu Li, Cai Xiao Feng, Ma Cui Qing
State Key Laboratory of Microbial Technology, Shandong University, Jinan 250100, People's Republic of China.
Trends Microbiol. 2006 Sep;14(9):398-405. doi: 10.1016/j.tim.2006.07.002. Epub 2006 Jul 24.
Sulfur (S), nitrogen (N) and oxygen (O) heterocycles are among the most potent environmental pollutants. Microbial degradation of these pollutants is attracting more and more attention because such bioprocesses are environmentally friendly. The biotechnological potential of these processes is being investigated, for example, to achieve better sulfur removal by immobilized biocatalysts with magnetite nanoparticles or by solvent-tolerant bacteria, and to obtain valuable intermediates from these heterocycles. Other recent advances have demonstrated the mechanisms of angular dioxygenation of nitrogen heterocycles by microbes. However, these technologies are not yet available for large-scale applications so future research must investigate proper modifications for industrial applications of these processes. This review focuses on recent progress in understanding how microbes degrade S, N and O heterocycles.
硫（S）、氮（N）和氧（O）杂环化合物是最具危害性的环境污染物之一。这些污染物的微生物降解因其环境友好性而受到越来越多的关注。人们正在研究这些过程的生物技术潜力，例如，通过使用负载有磁铁矿纳米颗粒的固定化生物催化剂或耐溶剂细菌来实现更好的脱硫效果，并从这些杂环化合物中获得有价值的中间体。最近的其他进展揭示了微生物对氮杂环化合物进行角双加氧反应的机制。然而，这些技术尚未应用于大规模生产，因此未来的研究必须探索对这些过程进行适当改进以用于工业应用。本综述重点关注了微生物降解硫、氮和氧杂环化合物方面的最新研究进展。
