Muangman Pornprom, Engrav Loren H, Heimbach David M, Harunari Nobuyuki, Honari Shari, Gibran Nicole S, Klein Matthew B
Burn Center, Department of Surgery, University of Washington, Harborview Medical Center, Seattle, WA 98104, USA.
Ann Plast Surg. 2006 Aug;57(2):199-202. doi: 10.1097/01.sap.0000218636.61803.d6.
The benefits of the Integra Dermal Regeneration Template in the management of extensive burn injuries have been well documented. Integra can reduce donor- and graft-site scarring and has been reported to be capable of vascularizing over small areas of exposed bone and tendon. Given these potential advantages, we have used Integra for a variety of other reconstruction applications. We performed a retrospective review of patients with complex wounds treated with Integra at our burn center. Integra was used in the management of a variety of wounds, including necrotizing fasciitis, extremity degloving injury, meningococcemia, Marjolin ulcer, postburn lip reconstruction, and fourth-degree burns with exposed bone or tendon. Engraftment rates of Integra and autograft were 98% +/- 4% and 97% +/- 4%, respectively. All areas of graft loss healed without need for regrafting. The benefits of Integra in the management of acute burn wounds can be extended to other traumatic and complex wounds.
Integra真皮再生模板在大面积烧伤治疗中的益处已有充分记录。Integra可减少供皮区和植皮区的瘢痕形成，并且据报道能够在小面积暴露的骨骼和肌腱上实现血管化。鉴于这些潜在优势，我们已将Integra用于各种其他重建应用。我们对在我们烧伤中心接受Integra治疗的复杂伤口患者进行了回顾性研究。Integra被用于治疗各种伤口，包括坏死性筋膜炎、肢体脱套伤、脑膜炎球菌血症、Marjolin溃疡、烧伤后唇部重建以及伴有暴露骨骼或肌腱的四度烧伤。Integra和自体移植的移植成功率分别为98%±4%和97%±4%。所有移植失败的区域均愈合，无需再次移植。Integra在急性烧伤伤口治疗中的益处可扩展至其他创伤性和复杂伤口。
