Campaner Adriana B, Scapinelli Alessandro, Machado Ruy O, Dos Santos Roberto E, Beznos Geni W, Aoki Tsutomu
Department of Obstetrics and Gynecology, Santa Casa São Paulo-Faculty of Medical Science, São Paulo, Brazil.
Gynecol Endocrinol. 2006 Jul;22(7):395-8. doi: 10.1080/09513590600819032.
We report a case of a prepubertal girl with juvenile primary hypothyroidism presenting as ovarian cysts and precocious puberty. The 7-year-old female was referred to our clinic because of a pelvic/abdominal mass and vaginal bleeding. Besides these findings, on physical examination we noticed the thyroid gland globally increased and the presence of secondary sexual characteristics. Based upon the clinical profile and investigations, the patient was diagnosed with juvenile primary hypothyroidism due to autoimmune thyroiditis. The cysts and precocious puberty resolved spontaneously after the simple replacement of thyroid hormone. It is important to bear in mind hypothyroidism in cases of girls presenting ovarian cysts and precocious puberty in order to avoid unnecessary surgery on the ovaries.
我们报告一例青春期前女童,患有青少年原发性甲状腺功能减退症,表现为卵巢囊肿和性早熟。这名7岁女性因盆腔/腹部肿块和阴道出血被转诊至我们的诊所。除了这些发现,体格检查时我们注意到甲状腺整体增大以及存在第二性征。根据临床特征和检查,该患者被诊断为自身免疫性甲状腺炎所致的青少年原发性甲状腺功能减退症。在单纯补充甲状腺激素后,囊肿和性早熟自行消退。对于出现卵巢囊肿和性早熟的女童病例,应牢记甲状腺功能减退症,以避免对卵巢进行不必要的手术。