Kubota Kazuko, Itho Masahiro, Kishi Hiroshi, Igarashi Shigeo, Minegishi Takashi
Department of Gynecology and Reproductive Medicine, Sub Division of Metabolic Regulation, Graduate School of Medicine, Gunma University, Gunma, Japan.
Gynecol Endocrinol. 2008 Oct;24(10):586-9. doi: 10.1080/09513590802288192.
A 21-year-old woman was referred because of abdominal pain. On physical examination, her abdomen was distended up to the umbilical region. Ultrasound and computer tomography of the abdomen revealed bilateral multiple ovarian cysts. Laboratory studies revealed increased liver function, total cholesterol and creatine phosphokinase. Further clinical investigations determined that the patient suffered from primary hypothyroidism due to autoimmune thyroiditis. The cysts resolved spontaneously after the simple replacement of a thyroid hormone. Some reports have been published of primary hypothyroidism presenting as ovarian cysts and precocious puberty in prepubertal girls. However, the case presented herein indicates that an ovarian tumor as a result of hypothyroidism may also occur in adult females. To avoid inadvertent surgery to remove an ovarian tumor, it is essential that a patient with multiple ovarian cysts and hypothyroidism be properly managed, as the simple replacement of a thyroid hormone could resolve the ovarian cysts.
一名21岁女性因腹痛前来就诊。体格检查发现其腹部膨胀至脐部区域。腹部超声和计算机断层扫描显示双侧多发性卵巢囊肿。实验室检查显示肝功能、总胆固醇和肌酸磷酸激酶升高。进一步的临床检查确定该患者因自身免疫性甲状腺炎患有原发性甲状腺功能减退症。在单纯补充甲状腺激素后，囊肿自行消退。已有一些关于原发性甲状腺功能减退症表现为青春期前女孩卵巢囊肿和性早熟的报道。然而，本文所报道的病例表明，甲状腺功能减退导致的卵巢肿瘤也可能发生在成年女性中。为避免无意中进行切除卵巢肿瘤的手术，对于患有多发性卵巢囊肿和甲状腺功能减退症的患者进行妥善管理至关重要，因为单纯补充甲状腺激素可能会使卵巢囊肿消退。
