Turcotte Simon, Dubé Serge, Beauchamp Gilles
Département de Chirurgie, Hôpital Maisonneuve-Rosemont, Centre affilié à I'Université de Montréal, 5415 boul de l'Assomption, Montréal, Quebec, H1T 2M4, Canada.
World J Surg. 2006 Aug;30(8):1605-19. doi: 10.1007/s00268-005-0174-y.
Peripherally inserted central venous catheters (PICC) have supplanted central venous catheters (CVC) for the administration of intravenous antibiotics and total parenteral nutrition to patients in our hospital. From the literature, it appears that this change has occurred in a number of other surgical units. Accounting for the change are the expected advantages of low complication rates at insertion, prolonged use without complications and interruption, and cost- and time-savings.
We have proceeded with a review of the literature to understand and justify this change in practice. Our hypothesis was that the routine adoption of PICC instead of CVC for the acute care of surgical patients has occurred in the absence of strong scientific evidence. Our aim was to compare the associated infectious, thrombotic, phlebitic, and other common complications, as well as PICC and CVC durability. Articles concerning various aspects of PICC- and CVC-related complications in the acute care of adult patients were selected from the literature. Studies were excluded when they primarily addressed the use of long-term catheters, outpatient care, and pediatric patients. Data were extracted from 48 papers published between 1979 and 2004.
Our results show that infectious complications do not significantly differ between PICC and CVC. Thrombotic complications appear to be more significant with PICC and to occur early after catheterization. Phlebitic complications accounted for premature catheter removal in approximately 6% of PICC. Finally, prospective data suggest that approximately 40% of PICC will have to be removed before completion of therapy, possibly more often and earlier than CVC.
We believe that there is no clear evidence that PICC is superior to CVC in acute care settings. Each approach offers its own advantages and a different profile of complications. Therefore, the choice of central venous access should be individualized for surgical patients on the ward. More comparative prospective studies are needed to document the advantages of PICC over CVC.
在我们医院,经外周静脉穿刺中心静脉置管(PICC)已取代中心静脉导管(CVC),用于为患者输注静脉抗生素和全胃肠外营养。从文献来看,其他一些外科科室也发生了这种转变。促成这种转变的原因是PICC预期具有以下优势:置管时并发症发生率低、可长期使用且无并发症和中断情况,还能节省成本和时间。
我们对文献进行了回顾,以理解并论证这种实践中的转变。我们的假设是,在缺乏有力科学证据的情况下,外科患者急性护理中常规采用PICC而非CVC。我们的目的是比较相关的感染、血栓形成、静脉炎及其他常见并发症,以及PICC和CVC的耐用性。从文献中选取了关于成年患者急性护理中PICC和CVC相关并发症各方面的文章。主要涉及长期导管使用、门诊护理和儿科患者的研究被排除。数据从1979年至2004年发表的48篇论文中提取。
我们的结果显示,PICC和CVC的感染并发症无显著差异。PICC的血栓形成并发症似乎更严重,且在置管后早期出现。静脉炎并发症导致约6%的PICC过早拔除。最后,前瞻性数据表明,约40%的PICC在治疗完成前必须拔除,可能比CVC更频繁、更早。
我们认为,没有明确证据表明在急性护理环境中PICC优于CVC。每种方法都有其自身优势和不同的并发症情况。因此,病房中外科患者的中心静脉通路选择应个体化。需要更多比较性前瞻性研究来证明PICC优于CVC的优势。