Jacquier Magali, Aarhaug Per, Arnemo Jon M, Bauer Hans, Enriquez Brigitte
Elephant Camp, BP 450 Garoua, Cameroon.
J Wildl Dis. 2006 Apr;42(2):432-6. doi: 10.7589/0090-3558-42.2.432.
A combination of medetomidine-tiletamine-zolazepam was used to conduct six immobilizations of free-ranging lions (Panthera leo) in Waza National Park, Cameroon, during 1999 and 2000. Drugs were administered by dart injection at 0.07+/-0.01 (mean+/-SD) mg/kg of medetomidine and 1.8+/-0.5 mg/kg of tiletamine-zolazepam. Chemical immobilization was characterized by smooth inductions (14.1+/-6 min), satisfactory analgesia, and muscle relaxation. One animal was treated for bradypnea. No major alterations of physiologic parameters (heart and respiratory rates, rectal temperature) were seen during immobilization in the other lions. Relative arterial oxygen saturation was measured in two animals and revealed mild hypoxemia. The animals received atipamezole at 0.3+/-0.1 mg/kg intramuscularly for reversal of anesthesia. Recoveries were uneventful. All animals were radiocollared, and no mortalities occurred during an 18-mo follow-up period. Use of medetomidine-tiletamine-zolazepam for anesthesia and reversal of anesthesia with atipamezole appear to be useful for reversible immobilization of free-ranging lions.
1999年至2000年期间，在喀麦隆的瓦扎国家公园，使用美托咪定-替来他明-唑拉西泮合剂对6只野生狮子（ Panthera leo ）进行了6次麻醉保定。通过飞镖注射给药，美托咪定剂量为0.07±0.01（均值±标准差）mg/kg，替来他明-唑拉西泮剂量为1.8±0.5 mg/kg。化学保定的特点是诱导平稳（14.1±6分钟）、镇痛效果良好且肌肉松弛。有1只动物出现呼吸过缓并接受了治疗。其他狮子在保定期间未观察到生理参数（心率、呼吸频率、直肠温度）的重大改变。对2只动物测量了动脉血氧饱和度，结果显示为轻度低氧血症。给动物肌肉注射0.3±0.1 mg/kg的阿替美唑以逆转麻醉。苏醒过程顺利。所有动物都佩戴了无线电项圈，在18个月的随访期内未发生死亡。美托咪定-替来他明-唑拉西泮用于麻醉以及用阿替美唑逆转麻醉，似乎对野生狮子的可逆性保定很有用。
