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肌醇(2-³H)掺入淋巴细胞磷脂酰肌醇与多发性硬化症残疾程度、分期及病程的相关性。

Correlation between incorporation of myo-(2-3H)inositol into the phosphatidylinositol of lymphocytes and disability degree, stage and duration of multiple sclerosis.

作者信息

Offner H, Fog T, Clausen J

出版信息

Acta Neurol Scand. 1975 Jul;52(1):1-6.

PMID:168718
Abstract

The present study revealed a positive correlation between the degree of disability of MS patients and the rate of incorporation of myo-(2-3-H)inositol into phosphatidylinositol of lymphocytes stimulated with basic protein (BP) and phytohemagglutinin (PHA). No correlation could be found between the response of lymphocytes to measles antigen (MA) and the degree of disability, stage and duration of multiple sclerosis. No correlation could be observed between the response of lymphocytes to the stimulants studied and the duration of the disease.

摘要

本研究揭示,多发性硬化症(MS)患者的残疾程度与用碱性蛋白(BP)和植物血凝素(PHA)刺激的淋巴细胞中肌醇 -(2-3-H)掺入磷脂酰肌醇的速率之间呈正相关。淋巴细胞对麻疹抗原(MA)的反应与多发性硬化症的残疾程度、阶段和病程之间未发现相关性。在所研究的刺激物作用下,淋巴细胞的反应与疾病持续时间之间未观察到相关性。

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