Takayama K, Miura M
Department of Physiology 1st Division, Gunma University School of Medicine, Maebashi, Japan.
Neurosci Lett. 1991 Dec 16;134(1):62-6. doi: 10.1016/0304-3940(91)90509-r.
Glutamate immunoreactivity was found in 9%, in the case of Wistar Kyoto rats (WKY), and 14%, in the case of spontaneously hypertensive rats (SHR), of neurons located in the medial division of the central amygdaloid nucleus (CeM) projecting ipsilaterally to the subretrofacial nucleus (SRF) in the rostral ventrolateral medulla using a double-labeling technique in combination with glutamate immunocytochemistry. The results indicate that possibly-glutamatergic neurons located in the CeM project to the SRF, in which vasomotor neurons are present, suggesting involvement of the CeM in blood pressure regulation. No significant difference was found between the distribution of labeled CeM neurons in SHR and WKY rats.
采用双重标记技术结合谷氨酸免疫细胞化学方法，发现在Wistar Kyoto大鼠（WKY）中，位于杏仁中央核内侧部（CeM）且向延髓头端腹外侧的面后核（SRF）同侧投射的神经元中，9%有谷氨酸免疫反应性；在自发性高血压大鼠（SHR）中，这一比例为14%。结果表明，位于CeM的可能为谷氨酸能的神经元投射至存在血管运动神经元的SRF，提示CeM参与血压调节。在SHR和WKY大鼠中，标记的CeM神经元分布无显著差异。
