Urassa M, Kumogola Y, Isingo R, Mwaluko G, Makelemo B, Mugeye K, Boerma T, Calleja T, Slaymaker E, Zaba B
Centre for Population Studies, London School of Hygiene and Tropical Medicine, 49-51 Bedford Square, London WC1B 3DP, UK.
Sex Transm Infect. 2006 Aug;82(4):301-6. doi: 10.1136/sti.2005.016766.
To assess the feasibility of collecting sexual behaviour data during HIV surveillance in antenatal care (ANC) clinics, and to establish whether these data can provide information about the correlates of HIV infection in this population.
Sexual behaviour surveys were conducted in the context of two HIV sentinel surveillance rounds in 11 ANC clinics in north west Tanzania between 2000 and 2002. Responses of individual women were anonymously linked to their HIV status. Three clinic catchment areas overlapped with a community based longitudinal study, which provided independent estimates of HIV prevalence and sexual behaviour. Changes between rounds and differentials between clinics were assessed and a two level logistic regression model used to identify behavioural and contextual correlates of HIV in 3689 women under 25 years of age.
Women attending clinics were willing to participate in the study. The sexual behaviour data obtained were internally consistent and tallied reasonably well with sexual behaviour data collected in the community overlapping the clinic catchment. Clear relations emerged between HIV infection and measures of sexual exposure: OR 1.20 (95% CL 1.12 to 1.28) for each year of premarital exposure and 1.09 (1.04 to 1.16) for each year after first marriage; background prevalence OR 1.15 (1.04 to 1.26) associated with each percentage point increase in background prevalence at the clinic; and certain partnership variables such as partner's age OR 0.58 (0.45 to 0.76) if partner less than 10 years older.
Conducting sexual behaviour surveys in the context of ANC clinics surveillance is feasible and yields useful data.
评估在产前保健（ANC）诊所的艾滋病病毒（HIV）监测期间收集性行为数据的可行性，并确定这些数据是否能提供有关该人群HIV感染相关因素的信息。
2000年至2002年期间，在坦桑尼亚西北部的11家ANC诊所进行了两轮HIV哨点监测，并开展了性行为调查。将个体女性的回答与其HIV状态进行匿名关联。三个诊所的服务区域与一项基于社区的纵向研究区域重叠，该研究提供了HIV流行率和性行为的独立估计值。评估两轮之间的变化以及诊所之间的差异，并使用二级逻辑回归模型确定3689名25岁以下女性中HIV的行为和背景相关因素。
到诊所就诊的女性愿意参与研究。获得的性行为数据在内部是一致的，并且与在诊所服务区域重叠的社区收集的性行为数据相当吻合。HIV感染与性暴露指标之间出现了明显的关系：婚前暴露每增加一年，比值比（OR）为1.20（95%可信区间[CL]为1.12至1.28），初婚后每增加一年为1.09（1.04至1.16）；诊所背景流行率每增加一个百分点，背景流行率的OR为1.15（1.04至1.26）；以及某些伴侣变量，如伴侣年龄小于10岁时，OR为0.58（0.45至0.76）。
在ANC诊所监测的背景下进行性行为调查是可行的，并能产生有用的数据。
