Redfield Robert R, Rickels Michael R, Naji Ali, Odorico Jon S
Division of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Clinical Science Cntr-H4/772, Madison, WI 53792, USA.
Division of Endocrinology, Diabetes & Metabolism, Department of Medicine, University of Pennsylvania Perelman School of Medicine, 2-134 Smilow Center for Translational Research, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA.
Gastroenterol Clin North Am. 2016 Mar;45(1):145-66. doi: 10.1016/j.gtc.2015.10.008. Epub 2016 Jan 13.
The field of pancreas transplantation has evolved from an experimental procedure in the 1980s to become a routine transplant in the modern era. With short- and long-term outcomes continuing to improve and the significant mortality, quality-of-life, and end-organ disease benefits, pancreas transplantation should be offered to more patients. In this article, we review current indications, patient selection, surgical considerations, complications, and outcomes in the modern era of pancreas transplantation.
胰腺移植领域已从20世纪80年代的一种实验性手术发展成为现代的常规移植手术。随着短期和长期疗效持续改善,以及在降低死亡率、提高生活质量和改善终末器官疾病方面的显著益处,应向更多患者提供胰腺移植。在本文中,我们回顾了现代胰腺移植时代的当前适应证、患者选择、手术考量、并发症及疗效。