Rajakumar Perumal, Rasheed A Mohammed Abdul, Balu P M, Murugesan K
Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai 600 025, India.
Bioorg Med Chem. 2006 Nov 15;14(22):7458-67. doi: 10.1016/j.bmc.2006.07.020. Epub 2006 Aug 1.
Synthesis of macrocyclic di, tetra- and hexaamides with aza and oxy linkages has been achieved and the inhibitory activity of cyclophane amides against human pathogenic bacteria well documented.
已实现含氮杂原子和氧原子连接的大环二酰胺、四酰胺和六酰胺的合成,并且环芳酰胺对人类病原菌的抑制活性已有充分记录。