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急性憩室炎的诊断与管理

Diagnosis and management of acute diverticulitis.

作者信息

Floch Craig L

机构信息

Norwalk Hospital, PC, 30 Stevens Street, Suite I, Norwalk, CT 06851, USA.

出版信息

J Clin Gastroenterol. 2006 Aug;40 Suppl 3:S136-44. doi: 10.1097/01.mcg.0000212609.59090.41.

Abstract

Although the diagnosis of acute diverticulitis is somewhat standardized, the scientific evidence and basis for treatment has been questioned. For years, medical and surgical management of acute diverticulitis has been based on the theory that more than 2 significant attacks of diverticulitis would lead to the recommendations of surgical resection. This should be questioned and further investigated with prospective randomized trials. Only a small number of well-published articles support the surgical management with good scientific data. Although our ability to take a history and skill of physical examination has not changed, the use of improved technology such as high-speed computerized axial tomography has afforded us the ability to make earlier and more accurate diagnoses. This may further allow us to standardize treatment and study outcomes. The time has come to further investigate and justify this management. It is possible that only the most critical situations may necessitate an operation. Clearly, the age group less than 40 years, as well as the immunocompromised, steroid-dependent, diabetic, and transplant patients, seem to be at greater risk with increased morbidity if not treated early and aggressively. And those individuals who present with perforation or compromised obstruction most likely will continue to need emergent intervention. We should try to set the rules by evidence-based medicine, while remaining within the confines of excellent and cost-effective care.

摘要

尽管急性憩室炎的诊断在一定程度上已标准化,但治疗的科学证据和依据受到了质疑。多年来,急性憩室炎的内科和外科治疗一直基于这样一种理论,即超过2次严重的憩室炎发作会导致建议进行手术切除。这一点应该受到质疑,并通过前瞻性随机试验进行进一步研究。只有少数发表充分的文章以良好的科学数据支持手术治疗。虽然我们问诊的能力和体格检查的技能没有改变,但高速计算机断层扫描等先进技术的应用使我们能够更早、更准确地做出诊断。这可能进一步使我们能够规范治疗并研究治疗结果。现在是进一步研究并证明这种治疗方法合理性的时候了。有可能只有最危急的情况才需要进行手术。显然,年龄小于40岁的人群,以及免疫功能低下、依赖类固醇、糖尿病和移植患者,如果不及早积极治疗,发病率似乎更高。而那些出现穿孔或严重梗阻的患者很可能仍需要紧急干预。我们应该尝试依据循证医学来制定规则,同时保持在优质且具有成本效益的医疗范围内。

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