Tomoda Chisato, Takamura Yuuki, Ito Yasuhiro, Miya Akihiro, Miyauchi Akira
Kuma Hospital, Kobe, Japan.
Thyroid. 2006 Jul;16(7):697-9. doi: 10.1089/thy.2006.16.697.
Complications of thyroid fine-needle aspiration biopsy (FNAB) are exceedingly rare. Hematoma formation is the most commonly encountered complication. Infection and seeding of carcinoma cells in the needle track has also been reported in a rare case. Here we describe patients diagnosed as having transient vocal cord paralysis after FNAB of benign thyroid tumor.
Retrospective review of patients with concurrent diagnosis of vocal cord paralysis after FNAB.
Among 10,974 patients who underwent FNAB, 4 patients showed vocal cord paralysis on laryngoscopy. These patients had solid and/or cystic lesion in the thyroid. Routine FNAB of the nodule was performed using a 23-gauge needle. Cytologic findings were benign tumor. Change of voice in the patients occurred 1 or 2 days after FNAB and vocal cord paralysis ipsilateral to FNAB was determined by flexible laryngoscopy. Vocal cord paralysis of all patients resolved spontaneously within 6 months (average, 4 months).
Although the incidence of vocal cord paralysis in patients with thyroid tumor after FNAB is reported to be 0.036%, the true incidence is unknown because asymptomatic subjects are not screened. This report should alert the examiner to the possibility of vocal cord palsy after FNAB.
甲状腺细针穿刺活检（FNAB）的并发症极为罕见。血肿形成是最常见的并发症。罕见情况下也有关于针道癌细胞感染和种植的报道。在此，我们描述了在良性甲状腺肿瘤FNAB后被诊断为短暂性声带麻痹的患者。
对FNAB后同时诊断为声带麻痹的患者进行回顾性研究。
在10974例行FNAB的患者中，4例患者经喉镜检查显示声带麻痹。这些患者甲状腺内有实性和/或囊性病变。使用23号针常规对结节进行FNAB。细胞学检查结果为良性肿瘤。患者在FNAB后1或2天出现声音改变，通过可弯曲喉镜检查确定为与FNAB同侧的声带麻痹。所有患者的声带麻痹在6个月内（平均4个月）自发缓解。
尽管据报道甲状腺肿瘤患者FNAB后声带麻痹的发生率为0.036%，但由于未对无症状者进行筛查，真实发生率尚不清楚。本报告应提醒检查者注意FNAB后发生声带麻痹的可能性。
