Rortveit Guri, Hunskaar Steinar
Section for General Practice, Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway.
Am J Obstet Gynecol. 2006 Aug;195(2):433-8. doi: 10.1016/j.ajog.2006.01.023. Epub 2006 Apr 21.
This study was undertaken to investigate the association between maternal age at the first and last delivery, and urinary incontinence later in life.
In the Norwegian EPINCONT study (a substudy of HUNT 2), cross-sectional data on incontinence from 11,397 women aged 20 to 64 years was linked with prospectively obtained data on exposures from the Medical Birth Registry of Norway. Bivariate and multivariate methods were applied.
Women 25 years or younger at their first delivery had a lower risk of incontinence than their older counterparts (23% vs 28%, P < .01). No significant effect of maternal age at the first delivery was found in women with actual age 50 to 64 years. Adjusting for confounders did not change any results. Age at the last delivery was less associated with incontinence.
Being older than 25 years at the first delivery was associated with incontinence. The effect attenuated with actual age.
本研究旨在调查首次分娩和末次分娩时的产妇年龄与晚年尿失禁之间的关联。
在挪威EPINCONT研究（HUNT 2的一项子研究）中，来自11397名年龄在20至64岁之间女性的尿失禁横断面数据与从挪威医疗出生登记处前瞻性获取的暴露数据相关联。应用了双变量和多变量方法。
首次分娩时年龄在25岁及以下的女性尿失禁风险低于年龄较大的女性（23%对28%，P <.01）。在实际年龄为50至64岁的女性中，未发现首次分娩时产妇年龄有显著影响。对混杂因素进行调整并未改变任何结果。末次分娩时的年龄与尿失禁的关联较小。
首次分娩时年龄超过25岁与尿失禁有关。这种影响随着实际年龄的增长而减弱。
