Kral Andrej, Tillein Jochen
Laboratories of Auditory Neuroscience, Institute of Neurophysiology and Pathophysiology, University of Hamburg, Hamburg, Germany.
Adv Otorhinolaryngol. 2006;64:89-108. doi: 10.1159/000094647.
The benefit of cochlear implantation crucially depends on the ability of the brain to learn to classify neural activity evoked by the cochlear implant. Brain plasticity is a complex property with massive developmental changes after birth. The present paper reviews the experimental work on auditory plasticity and focuses on the plasticity required for adaptation to cochlear implant stimulation. It reviews the data on developmental sensitive periods in auditory plasticity of hearing, hearing-impaired and deaf, cochlear-implanted, animals. Based on the analysis of the above findings in animals and comparable data from humans, a cochlear implantation within the first 2 years of age is recommended.
人工耳蜗植入的益处关键取决于大脑学习对人工耳蜗诱发的神经活动进行分类的能力。大脑可塑性是一种复杂的特性,出生后会发生大量的发育变化。本文回顾了关于听觉可塑性的实验研究,并重点关注适应人工耳蜗刺激所需的可塑性。它回顾了听力正常、听力受损和失聪、接受人工耳蜗植入的动物在听觉可塑性方面发育敏感期的数据。基于对动物上述研究结果以及来自人类的可比数据的分析,建议在2岁之前进行人工耳蜗植入。