Seif F E, Azar S, Barake M, Sawaya R
Department of Internal Medicine, American University of Beirut-Medical Center, Beirut, Lebanon.
Neuro Endocrinol Lett. 2006 Aug;27(4):547-8.
Hypercalcemia is commonly associated with cancer, occurring in around 10-20% of cancer patients. Hypercalcemia is usually related to solid and non-solid malignancies specifically breast cancer, lung cancer and multiple myeloma. Hypercalcemia has been reported to occur in association with astrocytomas, and uncommonly in gliomas. We report a case of a previously healthy man presenting with glioblastoma multiforme . He was found to have persistently elevated serum calcium and calcitriol with normal parathyroid function. This is the first reported case of hypercalcemia associated with glioblastoma multiforme.
高钙血症通常与癌症相关，约10%-20%的癌症患者会出现该症状。高钙血症通常与实体和非实体恶性肿瘤有关，特别是乳腺癌、肺癌和多发性骨髓瘤。据报道，高钙血症与星形细胞瘤有关，在神经胶质瘤中较少见。我们报告一例既往健康的男性，患有多形性胶质母细胞瘤。他被发现血清钙和骨化三醇持续升高，甲状旁腺功能正常。这是首例报道的与多形性胶质母细胞瘤相关的高钙血症病例。
