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周围神经切断对大鼠脊髓背角浅层中凝集素结合的影响。

The effect of peripheral nerve section on lectin binding in the superficial dorsal horn of the rat spinal cord.

作者信息

Plenderleith M B, Snow P J

机构信息

Department of Anatomy, University of Queensland, St. Lucia, Australia.

出版信息

Brain Res. 1990 Jan 15;507(1):146-50. doi: 10.1016/0006-8993(90)90534-i.

DOI:10.1016/0006-8993(90)90534-i
PMID:1689202
Abstract

The effect of peripheral nerve section on binding of the plant lectin soybean agglutinin (SBA) to the dorsal horn of the spinal cord has been investigated in the rat. Four, 15 and 43 days after unilateral sciatic nerve section no effect on SBA binding in the L4 segment of the spinal cord was apparent. However 90 days after nerve section a marked decline in SBA binding was observed. It is suggested that the long latency in effect on SBA binding may be due to the slow rate of utilisation of the SBA binding site.

摘要

在大鼠中研究了外周神经切断对植物凝集素大豆凝集素(SBA)与脊髓背角结合的影响。单侧坐骨神经切断后4天、15天和43天,脊髓L4节段的SBA结合未见明显影响。然而,神经切断90天后,观察到SBA结合显著下降。提示对SBA结合产生影响的延迟时间较长可能是由于SBA结合位点的利用速率较慢。

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